Keyvius Sampson was a fourth-round draft pick in 2009 for the San Diego Padres. The Reds selected the pitcher off waivers in January, and he made his major league debut in July in Cincinnati, striking out two Pirates batters in the eighth inning of a 15-5 win. He was then moved to the starting rotation and proceeded to start 12 games, finishing the season with a 2-6 record and 6.54 ERA, striking out 42 batters in just over 52 innings.